Pharmaceutical Perspectives of Cancer Therapeutics by Chikezie O. Madu, Yi Lu (auth.), Yi Lu, Ram I. Mahato (eds.) PDF

By Chikezie O. Madu, Yi Lu (auth.), Yi Lu, Ram I. Mahato (eds.)

ISBN-10: 1441901302

ISBN-13: 9781441901309

ISBN-10: 1441901310

ISBN-13: 9781441901316

Pharmaceutical views of melanoma Therapeutics provides a finished but easy-to-follow assessment of the rules, present development and state of the art of melanoma therapeutics. The complexity of melanoma calls for an built-in realizing from either melanoma biology and pharmaceutical dosage types and drug supply that allows you to warrant a profitable healing routine. This publication combines and merges the data from those facets. across the world acclaimed specialists with a multi-disciplinary historical past, together with scientists and clinicians from either academia and industries have contributed to this e-book to bridge the next parts among easy learn and medical software, pharmaceutical drug improvement methods and regulatory matters, drug layout and supply, laboratory and translational experimentation, advertising and postmarketing surveillance.

Main good points of the book:

  • Anticancer drug improvement and regulatory approaches.
  • Strategies to suppress tumor angiogenesis and metastasis, triumph over multi-drug resistance in melanoma, objective telomerase and apoptosis pathways.
  • Therapeutic techniques to hire monoclonal antibody and melanoma vaccines.
  • Introduction of latest recommendations comparable to melanoma stem cells and new applied sciences akin to nanobiotechnology, RNA interference, microRNA, and melanoma mobilephone gene profiling.
  • Use of lipids, polymers and peptides for drug supply and concentrating on to melanoma cells or particular organs.
  • Utilization of bioimaging and HIF-1 knockout animal versions in melanoma research.
  • Clinical trials designs and principles

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Technical Aspects of Toxicological Immunohistochemistry: by Syed A. Aziz, Rekha Mehta PDF

By Syed A. Aziz, Rekha Mehta

ISBN-10: 1493915150

ISBN-13: 9781493915156

ISBN-10: 1493915169

ISBN-13: 9781493915163

This authoritative quantity examines immunohistochemical equipment aimed toward investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. 11 accomplished chapters supply pathologists and researchers in quite a few sub-disciplines of toxicology with a accomplished overview of the tools and techniques for immunohistochemical staining in numerous goal tissues. It explores the tissue-antigen and antibody-specific difficulties that could be encountered through the staining approaches and supply capability avenues for resolving quite a few methodological matters. certain realization is paid to the most recent enhancement systems for antigen retrieval and visualization in addition to snapshot research and antigen quantification. Written via top researchers in toxicology and pathology, this publication is an important source for toxicologists and pathologists operating with rodents, monkeys and aquatic animal tissues.

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Download e-book for iPad: Toxicological profiles - Methyl tert-butyl ether by Unknown

By Unknown

This e-book was once digitized and reprinted from the collections of the collage of California Libraries. It was once made out of electronic photos created in the course of the libraries’ mass digitization efforts. The electronic photographs have been wiped clean and ready for printing via computerized procedures. regardless of the cleansing technique, occasional flaws should be current that have been a part of the unique paintings itself, or brought in the course of digitization. This e-book and thousands of others are available on-line within the HathiTrust electronic Library at www.hathitrust.org.

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Blockbuster Drugs: The Rise and Decine of the Pharmaceutical - download pdf or read online

By Jie Jack Li

Blockbuster drugs-each of which generates greater than one billion money a yr in revenue-have revolutionized the because the early Eighties, whilst revenues of Tagamet on my own reworked a minor Philadelphia-based enterprise into the world's ninth-largest pharmaceutical corporation. In Blockbuster medications, Jie Jack Li tells the attention-grabbing tales at the back of the invention and improvement of those hugely profitable drugs, whereas additionally exploring the tumult the now faces because the "patent cliff" nears.

Having spent such a lot of his occupation in drug learn and improvement, Li brings an insider's eye to the narrative as he recounts the stories of discovery at the back of such medicines as Tagamet, Zantac, Claritin, Prilosec, Nexium, Serouquel, Plavix, and Ambien. As he discusses each one leap forward, Li additionally exhibits that clinical study is full of human drama-serendipitous discoveries, unexpected insights, demanding confrontations. for example, the writer tells of James Black, who continued within the learn that resulted in Tagamet-and that will eventually win him a Nobel Prize-despite strain from most sensible executives to pursue "more ecocnomic" paintings. The ebook indicates how examine at the back of Prilosec mixed creativity, overseas cooperation, and luck-the turning aspect being an opportunity come across of yank and Swedish scientists at a convention in Uppsala. There also are stories of magnificent rewards—George Rieveschl, the chemist who invented Benadryl, made a fortune on royalties-and of unjust truffles. eventually, Li indicates that for the world's biggest prescription drug brands, contemporary years were harrowing, as many well known medicinal drugs have come off patent within the U.S. industry, that means 1000's of billions of greenbacks in misplaced profit.

Anyone who enjoys stories of clinical discovery, or is concerned about the historical past at the back of the prescriptions they take, or desires a revealing inside of examine the pharmaceutical will locate this e-book really worth examining.

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Toxicological profiles - Hydrazines - download pdf or read online

By Unknown

This booklet was once digitized and reprinted from the collections of the college of California Libraries. It was once made from electronic photos created during the libraries’ mass digitization efforts. The electronic pictures have been wiped clean and ready for printing via computerized methods. regardless of the cleansing procedure, occasional flaws should be current that have been a part of the unique paintings itself, or brought in the course of digitization. This booklet and millions of others are available on-line within the HathiTrust electronic Library at www.hathitrust.org.

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Get Deja Review Pharmacology (2nd Edition) PDF

By Jessica Gleason

ISBN-10: 0071627294

ISBN-13: 9780071627290

Greatest RETENTION—MINIMAL TIME

"]This is a wonderful evaluate of pharmacology for the coed who's seeking to determine his/her strengths and weaknesses sooner than the exam." — Alexis Dallara, Fourth 12 months clinical scholar, SUNY Downstate university of Medicine

"The fantastic thing about this article is that it comprises crucial pharmacology options in a compact publication that may be quick referenced and browse a number of instances throughout the process a student's stories. i'd certainly suggest it to any clinical student." — Rosalyn Pham, Fourth 12 months scientific scholar, collage of Washington clinical School

Deja assessment: Pharmacology boils down your coursework to simply the serious ideas you want to comprehend for examination good fortune. This unbeatable advisor incorporates a quick-read, two-column "flashcard" Q&A format—specifically designed that will help you keep in mind a large number of pertinent details the least bit period of time attainable.

The structure lets you zero-in on simply the proper solutions to advertise reminiscence retention and get the main from your research time. nice for final minute evaluate of high-yield proof, Deja Review presents a simple approach so you might verify your strengths and weaknesses so that you can excel in your path assessments and the USMLE Step 1.

• lively keep in mind questions let you understand, not only memorize, the content
• medical vignettes on the finish of chapters arrange you for board-style questions
• moveable measurement for research at the go—fits on your white coat pocket
• Bookmark integrated to steer you thru easy-to-use flashcard presentation

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Akute und therapieresistente Depressionen: Pharmakotherapie - download pdf or read online

By Michael Bauer, Anne Berghöfer, Mazda Adli

ISBN-10: 3540406174

ISBN-13: 9783540406174

Das tiefe Tal ?berwinden!

Depressionen geh?ren zu den h?ufigsten psychiatrischen Krankheitsbildern. Therapiem?glichkeiten gibt es viele, und meistens haben sie auch Erfolg. used to be aber tun, wenn sich eine melancholy als therapieresistent, extrem langanhaltend oder st?ndig wiederkehrend erweist? Einfach weiterprobieren – oder praktische Hilfe suchen?

Die Neuauflage der Therapieresistenten Depressionen beantwortet Ihre Fragen:

Was sind die Ursachen, und wie definiert guy eine therapieresistente melancholy?

Welche weiteren pharmakologischen und nichtpharmakologischen Behandlungsm?glichkeiten gibt es?

Wie sollte der Gesamtbehandlungsplan aussehen?

Welche Zukunftsperspektiven er?ffnen sich?

Hier finden Sie praktische Anleitungen und Leitlinien f?r Ihren Therapieplan und profitieren von den neuesten Forschungsergebnissen eines internationalen Autorenteams.

So entwickeln Sie die optimalen Behandlungsstrategien f?r Ihre Patienten!

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Download e-book for iPad: Adverse Drug Reactions by Michael Holt, Cynthia Ju (auth.), Jack Uetrecht (eds.)

By Michael Holt, Cynthia Ju (auth.), Jack Uetrecht (eds.)

ISBN-10: 3642006620

ISBN-13: 9783642006623

This e-book offers the present country of data of uncomplicated mechanisms of inauspicious drug reactions (ADRs). the main target is on idiosyncratic drug reactions simply because they're the main tricky to house. It starts off with a basic description of the key objectives for ADRs by way of an outline of what are almost immediately believed to be mediators and biochemical pathways taken with idiosyncratic drug reactions. there's additionally an outline of a number of examples of ADRs that serve to demonstrate particular facets of ADR mechanisms. finally the publication indicates that finally larger equipment are had to expect which drug applicants tend to reason ADRs and which sufferers are at elevated chance. yet at the moment study appears faraway from this goal.

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